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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK3
All Species:
18.79
Human Site:
Y285
Identified Species:
25.83
UniProt:
Q00526
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00526
NP_001249.1
305
35046
Y285
K
T
A
L
A
H
P
Y
F
S
S
P
E
P
S
Chimpanzee
Pan troglodytes
XP_523720
325
36841
Y305
K
T
A
L
A
H
P
Y
F
S
S
P
E
P
S
Rhesus Macaque
Macaca mulatta
XP_001102596
305
34903
Y285
K
T
A
L
A
H
P
Y
F
S
S
P
E
P
S
Dog
Lupus familis
XP_540442
303
34173
Y283
K
A
A
L
V
H
P
Y
F
S
S
A
E
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80YP0
303
33870
Y284
K
T
A
L
A
H
P
Y
F
S
P
G
H
S
L
Rat
Rattus norvegicus
Q63699
298
33869
A277
D
P
N
K
R
I
S
A
K
A
A
L
A
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
H284
S
G
K
M
A
L
N
H
P
Y
F
D
D
L
D
Frog
Xenopus laevis
P23437
297
33852
A277
D
S
N
K
R
I
S
A
K
V
A
L
T
H
P
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
A277
D
P
N
K
R
I
S
A
K
N
A
L
V
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
S277
Y
D
P
V
H
R
I
S
A
K
D
I
L
E
H
Honey Bee
Apis mellifera
XP_393450
299
34033
G279
Q
R
I
T
A
K
K
G
L
S
H
P
Y
F
N
Nematode Worm
Caenorhab. elegans
P34556
332
38277
Y311
K
K
A
L
V
H
P
Y
F
D
N
M
D
T
S
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
A277
E
P
D
K
R
I
S
A
K
T
G
L
S
H
P
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
D271
L
S
K
M
L
F
L
D
P
T
K
R
I
T
A
Maize
Zea mays
P23111
294
33816
E271
L
S
K
M
L
R
Y
E
P
S
K
R
I
T
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
D271
L
S
K
M
L
L
M
D
P
T
K
R
I
N
A
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
D279
L
D
K
L
L
A
Y
D
P
I
N
R
I
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96.7
88.5
N.A.
82.6
74.7
N.A.
N.A.
63.6
73.7
73.7
N.A.
62.9
67.2
58.1
69.5
Protein Similarity:
100
93.5
98.3
92.7
N.A.
91.8
84.5
N.A.
N.A.
78
84.5
83.2
N.A.
76.7
80.6
69.5
82.6
P-Site Identity:
100
100
100
73.3
N.A.
66.6
0
N.A.
N.A.
6.6
0
0
N.A.
0
20
53.3
0
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
13.3
N.A.
N.A.
26.6
13.3
13.3
N.A.
6.6
33.3
66.6
13.3
Percent
Protein Identity:
65.2
64.2
N.A.
65.5
62.3
N.A.
Protein Similarity:
81.6
80.9
N.A.
81.3
77.7
N.A.
P-Site Identity:
0
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
36
0
36
6
0
24
6
6
18
6
6
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
12
6
0
0
0
0
18
0
6
6
6
12
0
6
% D
% Glu:
6
0
0
0
0
0
0
6
0
0
0
0
24
6
0
% E
% Phe:
0
0
0
0
0
6
0
0
36
0
6
0
0
6
0
% F
% Gly:
0
6
0
0
0
0
0
6
0
0
6
6
0
0
0
% G
% His:
0
0
0
0
6
36
0
6
0
0
6
0
6
24
6
% H
% Ile:
0
0
6
0
0
24
6
0
0
6
0
6
24
0
0
% I
% Lys:
36
6
30
24
0
6
6
0
24
6
18
0
0
0
0
% K
% Leu:
24
0
0
42
24
12
6
0
6
0
0
24
6
6
6
% L
% Met:
0
0
0
24
0
0
6
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
18
0
0
0
6
0
0
6
12
0
0
6
6
% N
% Pro:
0
18
6
0
0
0
36
0
30
0
6
24
0
18
18
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
6
0
0
24
12
0
0
0
0
0
24
0
0
6
% R
% Ser:
6
24
0
0
0
0
24
6
0
42
24
0
6
12
30
% S
% Thr:
0
24
0
6
0
0
0
0
0
18
0
0
6
24
0
% T
% Val:
0
0
0
6
12
0
0
0
0
6
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
12
36
0
6
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _